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Opentargets MCP Server

@Augmented-Nature

リポジトリ

基本情報

カテゴリ

データと分析

トランスポート

stdio

作者

Augmented-Nature

投稿者

Moudather Chelbi

Opentargets MCP Server について

Unofficial Model Context Protocol server for accessing Open Targets platform data for gene-drug-disease associations research.

#opentargets#gene-drug-disease#research

Opentargets MCP Server の設定

以下の設定を使って、このサーバーを MCP 対応クライアントに追加してください。

{
  "mcpServers": {
    "OpenTargets-MCP-Server": {
      "command": "node",
      "args": [
        "build/index.js"
      ]
    }
  }
}

Opentargets MCP Server のツール

ツール一覧はまだありません

この掲載には表示できるツール一覧がまだありません。サーバーにツールがないという意味ではありません。対応機能はプロジェクトのドキュメントをご確認ください。

ツールは README から自動的に抽出されます。メンテナーは ## Tools という見出しの下に記載することで、このタブに反映できます。

概要

What is Opentargets Mcp Server?

An unofficial Model Context Protocol server for accessing Open Targets platform data to research gene-drug-disease associations. Developed by Augmented Nature, it provides six tools that query live Open Targets API data.

How to use Opentargets Mcp Server?

Install and build with npm install && npm run build, then run node build/index.js. Configure in MCP clients such as Claude Desktop by adding a JSON entry pointing to the built server script.

Key features of Opentargets Mcp Server

  • Six verified tools working with live Open Targets API data
  • Target and disease search with size control (1–500 results)
  • Target-disease associations with evidence scores from 20+ databases
  • Comprehensive gene/protein and disease profile details
  • Resource templates using standardized URIs
  • GraphQL-based queries with no authentication required

Use cases of Opentargets Mcp Server

  • Cancer research workflow: search oncogenes, retrieve target details, find associated diseases, and get prioritized targets
  • Drug discovery pipeline: search for diseases, retrieve disease profiles, and identify therapeutic targets

よくある質問

1

What runtime does Opentargets Mcp Server require?

Node.js is required to run the server, as it is built and executed using `npm` and `node` commands.

2

Does Opentargets Mcp Server require authentication?

No, the Open Targets API does not require authentication and offers generous rate limits for research use.

3

What data sources does Opentargets Mcp Server use?

It integrates over 20 databases including ChEMBL, Ensembl, EFO, ClinVar, GWAS Catalog, UniProt, and Reactome.

4

How is data accessed in Opentargets Mcp Server?

Data is retrieved via GraphQL queries to the Open Targets platform API v4 (`api.platform.opentargets.org/api/v4/graphql`) using standardized identifiers (Ensembl gene IDs, EFO IDs, ChEMBL IDs).

5

Are there any known limits of Opentargets Mcp Server?

The README notes generous rate limits for research use but does not specify exact caps; tools have a default result size of 25 (max 500).

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