Geneontology MCP Server

What is Geneontology Mcp Server?

Geneontology Mcp Server is an unofficial Model Context Protocol server that provides AI systems with access to Gene Ontology (GO) data. It enables ontology-based analysis, gene annotation research, and functional enrichment studies by integrating with the QuickGO API and the GO Consortium.

How to use Geneontology Mcp Server?

Install with npm install && npm run build, then add the built index.js to your MCP client configuration as a command‑line server. Use the provided tools (search_go_terms, get_go_term, validate_go_id, get_ontology_stats) and resource templates (go://term/{id}, go://annotations/{gene}, go://search/{query}, go://hierarchy/{id}) to interact with GO data.

Key features of Geneontology Mcp Server

• Search GO terms by keyword, name, or definition
• Retrieve detailed information for a specific GO term
• Validate GO identifiers and check term existence
• Navigate hierarchical relationships between ontology terms
• Access GO annotations for genes and proteins
• Obtain ontology statistics and metadata

Use cases of Geneontology Mcp Server

• AI‑powered literature review requiring GO term lookups and definitions
• Automated functional enrichment analysis of gene lists
• Validating GO identifiers in large‑scale bioinformatics pipelines
• Exploring ontology hierarchies to identify parent‑child term relationships
• Retrieving gene annotations for genomic research and curation