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Opentargets MCP Server

@Augmented-Nature

代码仓库

基本信息

分类

数据与分析

传输方式

stdio

作者

Augmented-Nature

提交者

Moudather Chelbi

关于 Opentargets MCP Server

Unofficial Model Context Protocol server for accessing Open Targets platform data for gene-drug-disease associations research.

#opentargets#gene-drug-disease#research

Opentargets MCP Server 配置

使用下面的配置,将此服务器添加到你的 MCP 客户端。

{
  "mcpServers": {
    "OpenTargets-MCP-Server": {
      "command": "node",
      "args": [
        "build/index.js"
      ]
    }
  }
}

Opentargets MCP Server 工具

工具列表暂未提供

当前收录暂时没有可展示的工具列表，不代表服务没有工具。请查阅项目文档了解支持的能力。

工具是从 README 中自动提取的。维护者可以在 ## Tools 标题下列出工具,即可填充这部分内容。

概览

What is Opentargets Mcp Server?

An unofficial Model Context Protocol server for accessing Open Targets platform data to research gene-drug-disease associations. Developed by Augmented Nature, it provides six tools that query live Open Targets API data.

How to use Opentargets Mcp Server?

Install and build with npm install && npm run build, then run node build/index.js. Configure in MCP clients such as Claude Desktop by adding a JSON entry pointing to the built server script.

Key features of Opentargets Mcp Server

  • Six verified tools working with live Open Targets API data
  • Target and disease search with size control (1–500 results)
  • Target-disease associations with evidence scores from 20+ databases
  • Comprehensive gene/protein and disease profile details
  • Resource templates using standardized URIs
  • GraphQL-based queries with no authentication required

Use cases of Opentargets Mcp Server

  • Cancer research workflow: search oncogenes, retrieve target details, find associated diseases, and get prioritized targets
  • Drug discovery pipeline: search for diseases, retrieve disease profiles, and identify therapeutic targets

常见问题

1

What runtime does Opentargets Mcp Server require?

Node.js is required to run the server, as it is built and executed using `npm` and `node` commands.

2

Does Opentargets Mcp Server require authentication?

No, the Open Targets API does not require authentication and offers generous rate limits for research use.

3

What data sources does Opentargets Mcp Server use?

It integrates over 20 databases including ChEMBL, Ensembl, EFO, ClinVar, GWAS Catalog, UniProt, and Reactome.

4

How is data accessed in Opentargets Mcp Server?

Data is retrieved via GraphQL queries to the Open Targets platform API v4 (`api.platform.opentargets.org/api/v4/graphql`) using standardized identifiers (Ensembl gene IDs, EFO IDs, ChEMBL IDs).

5

Are there any known limits of Opentargets Mcp Server?

The README notes generous rate limits for research use but does not specify exact caps; tools have a default result size of 25 (max 500).

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