What is CovaSyn?
CovaSyn gives AI assistants (Claude, ChatGPT, Cursor, VS Code and any MCP client) real chemistry tools. Instead of guessing, the model calls deterministic calculations and gets results you can check.
What you can do
- Spectra: NMR assignment and prediction, mass spectrometry (formula, fragments, impurities, metabolites), IR and UV analysis
- Safety and regulatory: ADMET, toxicity screening, ICH M7 mutagenicity assessment, structural alerts
- Stability: shelf-life estimation, Arrhenius fitting, OOT/OOS detection (ICH Q1)
- Analytical methods: HPLC method scouting, column selection, USP <621> checks
- Development: DoE design and analysis, solubility and crystallisation, retrosynthesis, docking, structure prediction
- Biologics: antibody developability, peptides, oligos, mRNA and LNP formulation
Why it matters
On MolecularIQ, an independent public chemistry benchmark (preprint arXiv:2601.15279, Klambauer Lab, JKU Linz), AI models alone reached 14 to 41% on chemical structure tasks. With CovaSyn tools they reached 76 to 92%. Details: https://covasyn.com/en/benchmark
Connect
Endpoint: https://mcp.covasyn.com/mcp (Streamable HTTP). Sign in with OAuth or use an API key from https://workspace.covasyn.com. Setup guides: https://covasyn.com/en/docs/mcp
Try the free Sketcher without sign-up: https://covasyn.com/en/sketcher
Built by chemists in Leipzig, Germany. Structures are processed on servers in Germany.
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