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Appendix MCP Server

@appendixhealth

Repository

Basic information

Category

AI & Agents

Transports

stdio

Author

appendixhealth

Submitted by

Benjamin Jack

About Appendix MCP Server

Appendix turns any AI health conversation into a board-certified physician's opinion — with a real prescription when clinically appropriate. Search medical literature and submit a clinical encounter for review, all from your agent.

#healthcare#medical#telemedicine#prescriptions#clinical#health

Appendix MCP Server config

Add this server to your MCP-compatible client using the configuration below.

{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Appendix MCP Server tools

3

Search Appendix's medical knowledge base for clinical literature, treatment guidelines, and reference material to help the user describe their medical issue

Submit a clinical encounter letter to the Appendix physician team for review. The letter should be in Markdown format following the Appendix letter structure. Returns feedback on completeness or a checkout URL when ready. One of our board-certified physicians will personally review the submission and provide clinical guidance and a prescription if appropriate.

List all conditions and medications available through Appendix

Overview

What is Appendix?

Appendix is an MCP server that enables AI agents to transform health conversations into board-certified physician reviews and, when clinically appropriate, prescriptions. It integrates with the Appendix API to search peer-reviewed medical literature, draft structured clinical letters, and submit them for physician review.

How to use Appendix?

Add the server via claude mcp add --transport http appendix https://mcp.appendix.com/mcp for Claude Code, or configure it in your mcpServers JSON for Claude Desktop. Then call the available tools like search_knowledge_base, submit_encounter, or list_conditions from your AI agent.

Key features of Appendix

  • Searches peer-reviewed medical literature and treatment guidelines.
  • Drafts and submits structured clinical letters for physician review.
  • Provides board-certified physician opinions with prescriptions when appropriate.
  • Knowledge Base access is free; clinical services require a paid subscription.
  • No signup required to start using the API.
  • Lists available conditions and medications via list_conditions.

Use cases of Appendix

  • An AI assistant helps a user describe symptoms, then searches medical literature and drafts a clinical letter for physician review.
  • A user receives a prescription for a common condition after a physician reviews the encounter submitted via the Appendix API.
  • A developer integrates the MCP server into a health-focused AI application to provide evidence-based information and referral to clinical services.

Frequently asked questions

1

Does Appendix require a subscription to use?

The Knowledge Base is free for everyone. Clinical services (physician review and prescriptions) require a paid subscription and are currently available only in supported US states.

2

Do I need to sign up to use the API?

No signup is required to start using the Appendix API.

3

What transport protocol does the server use?

The MCP server uses HTTP transport as shown in the installation examples.

Comments

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