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23andme Raw Data File Lookup MCP Server

@obuchowski

Repository

Basic information

Category

Data & Analytics

Transports

stdio

Author

obuchowski

Submitted by

Evgeni Obuchowski

About 23andme Raw Data File Lookup MCP Server

Querying genotype data by RSID from 23andMe raw file

#23andme#raw#rsid#genotype#snp

23andme Raw Data File Lookup MCP Server config

Add this server to your MCP-compatible client using the configuration below.

{
  "mcpServers": {
    "23andMe Genotype Lookup": {
      "command": "node",
      "args": [
        "~/src/index.js",
        "~/sample-data.txt"
      ]
    }
  }
}

23andme Raw Data File Lookup MCP Server tools

Tool list not available yet

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Overview

What is 23andme Raw Data File Lookup?

A Model Context Protocol server that enables LLMs to query 23andMe raw genotype files by RSID (Reference SNP cluster ID). It parses TSV-formatted 23andMe raw data files and provides instant access to genetic information for research and educational purposes.

How to use 23andme Raw Data File Lookup?

Install via npm after cloning the repository, then configure the server in your MCP client (e.g., Claude.app or Zed) by specifying the command node with arguments pointing to the server script and your 23andMe raw data file. Once running, you can ask an LLM to look up genotypes using the get_genotype_by_rsid tool with an RSID string.

Key features of 23andme Raw Data File Lookup

  • Parses 23andMe raw TSV genotype files.
  • Looks up genotype by Reference SNP cluster ID.
  • Runs entirely locally, no external data transmission.
  • Read-only access, never modifies genetic data.
  • Integrates with LLMs through Model Context Protocol.
  • Simple installation via npm with Node.js v18+.

Use cases of 23andme Raw Data File Lookup

  • Look up specific genetic variants from your 23andMe data via an LLM.
  • Answer personal genetic questions like “What is my genotype for rs1234567?”
  • Check if you have a particular variant (e.g., rs1815739) for educational exploration.
  • Research into associations between multiple RSIDs and phenotypes.

Frequently asked questions

1

What data format does the server expect?

The server expects standard 23andMe raw data files in TSV format with columns rsid, chromosome, position, and genotype, and ignores header lines starting with `#`.

2

Does the server send my genetic data externally?

No. All processing is done locally on your machine; the server only reads your local data file and never transmits genetic information.

3

How do I get a 23andMe raw data file to use with this server?

Log into your 23andMe account, go to Settings → Privacy → Download Data, request and download your raw genetic data, then provide the file path to the server.

4

What are the prerequisites for running this server?

Node.js v18 or

Comments

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